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Updated: May 11, 2026

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具有肝脏参与的病动物模型

Oluwashanu Balogun1, Kari Nejak-Bowen1,2,3

  • 1Organ Pathobiology and Therapeutics Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

Seminars in liver disease
|August 21, 2025
PubMed
概括

动物模型对于了解波菲利亚,影响血红蛋白合成的罕见代谢障碍至关重要. 这篇评论详细介绍了肝脏的模型,有助于研究疾病机制和新疗法.

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In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...