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Updated: Sep 10, 2025

Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors
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Published on: July 17, 2020

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在棕植物性 pustulosis 的 Janus 激酶抑制剂:混合方法可行性试验 (JAKPPPOT) 协议

David Gleeson1, Sarah Chapman2, Helen McAteer3

  • 1St. John's Institute of Dermatology, Guy's & St. Thomas' NHS Foundation Trust and King's College London, London, UK.

BMJ open
|August 21, 2025
PubMed
概括

这项研究评估了使用Janus激酶 (JAK) 抑制剂的可行性,如upadacitinib,用于治疗棕植物性 pustulosis (PPP). 这些结果将指导未来对PPP患者的JAK抑制剂疗效和安全性的随机对照试验.

关键词:
成人皮肤病学临床试验可行性研究牛皮

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