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Updated: Sep 10, 2025

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma
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VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma

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人体免疫球蛋白重链位点连续单元型解析的超长测序

Mari B Gornitzka1, Egil Røsjø2, Uddalok Jana3

  • 1University of Oslo.

Genome research
|August 21, 2025
PubMed
概括

研究人员开发了一种测序人类免疫球蛋白重链 (IGH) 位点的新方法,揭示了新的遗传变异. 这一突破提高了我们对免疫功能和疾病易感性的理解.

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Multi-species Conserved Sequences02:51

Multi-species Conserved Sequences

Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
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