术前计算机断层扫描功能作为恶性瘤和上腺癌的生存预测
William L Snell1, Ashton Cole Berger1, Elisa Spoldi2
1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.
Veterinary and comparative oncology
|August 21, 2025
概括
在患有上腺瘤的狗中,计算机断层扫描 (CT) 显示没有预测恶性或生存的特定成像特征. 脊髓切除术,年龄较大和同时进行尿路切除术对狗上腺瘤患者的长期结果产生影响.
科学领域:
- 兽医放射学
- 狗类瘤学
- 比较病理学
背景情况:
- 计算机断层扫描 (CT) 越来越多地用于犬上腺瘤分期和手术规划.
- 关于恶性上腺瘤的CT特征及其与生存相关性的数据有限.
- 本研究旨在通过分析有关恶性瘤和预后的CT发现来弥补这一差距.
研究的目的:
- 评估与恶性上腺瘤相关的手术前CT特征.
- 确定CT特征与上腺瘤患者的生存时间缩短相关.
- 为物主人提供有关手术结果的预后信息.
主要方法:
- 对201只在单一第三级护理机构治疗的226只上腺瘤进行了回顾性分析.
- 盲目放射科医生对CT扫描进行了审查,结果与组织病理学和生存数据相关.
- 用多变量分析来确定生存的预测因素.
主要成果:
- 上腺瘤的总生存时间中位数为671天.
- 单侧上腺切除术与双侧上腺切除术 (697 vs.
- 恶性组织病理诊断与较短的存活时间 (952 vs 1514天) 没有显著的相关性.
- 没有CT特征预测了长期存活的缩短.
- 在多变量分析中,切除术 (不包括早期的术后死亡),年龄较大和同时进行的尿路切除术是死亡率的显著预测因素.
结论:
- 在患有上腺瘤的狗中,手术前CT特征不能可靠地预测恶性瘤或存活率.
- 脊髓切除术,患者年龄和并发手术等因素显著影响长期存活.
- 这些发现为兽医和物主人提供了有价值的预后见解.
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