与年龄相关的声缩和帕金森病患者的诊断声增大
Isabela H Schettini1, Brett A Campbell2, Victoria Flormann3
1Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, Brigham and Women's Hospital, Boston, Massachusetts.
Journal of voice : official journal of the Voice Foundation
|August 21, 2025
概括
在帕金森病 (PD) 患者中,临时的声增强改善了声音障碍. 这项研究评估了语音障碍指数-10 (VHI) 的变化,显示了主观和客观的好处.
科学领域:
- 耳鼻喉科
- 神经学
- 语音病理学
背景情况:
- 帕金森病 (PD) 可能导致喉功能不充分,影响语音质量并导致语音障碍.
- 对于PD患者,特别是与年龄相关的声缩患者的喉功能缺陷的干预措施的有效性需要进一步研究.
- 对PD语音障碍的客观结果措施是有限的.
研究的目的:
- 评估临时声注射增强对患有帕金森病和与年龄相关的真声缩患者的声音障碍的影响.
- 在程序后评估语音障碍指数-10 (VHI) 得分的变化.
- 探索患者自我报告的结果和进展到永久增强.
主要方法:
- 对被诊断患有PD和与年龄相关的真实声缩的患者进行了临时声注射增大.
- 在手术前和后收集了语音障碍指数-10 (VHI) 评分.
- 记录了患者对改善的自我印象和随后的程序.
主要成果:
- 其中包括17名患者 (平均年龄为68. 4岁),在注射前患有喉功能不全,平均VHI得分为26. 1.
- 82. 35% 的患者报告主观声音改善 (P=0. 03).
- 在注射后,58. 82%的患者的VHI-10得分有客观改善. 47%的人进行了永久增强.
结论:
- 暂时的声注射增大为帕金森病患者提供主观和客观的好处,因为与年龄相关的声缩导致的喉功能不充分.
- 这些发现支持使用临时增强作为这种患者群体的可行选择.
- 需要对PD患者永久增强手术的长期结果进行进一步的研究.
相关概念视频
Parkinson's Disease: Treatment
377
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
377
Parkinson's Disease: Overview
703
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
703
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.6K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.6K
Pulmonary Function Tests
433
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
433
Respiratory System Abnormal Finding II: Palpation and Auscultation
733
In assessing respiratory abnormalities, palpation and auscultation are critical tools for detecting and interpreting various pathophysiological changes. These techniques provide insight into underlying disorders by evaluating tactile sensations and sounds produced by the respiratory system.
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
733
Larynx
2.1K
The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
2.1K


