相关实验视频
Updated: May 9, 2026

06:47
A Murine Model of Vertical Sleeve Gastrectomy
Published on: December 18, 2017
11.2K
在217名患者中进行的多机构研究
Georges Kaoukabani1, Amin Andalib2, Romulo Lind3
1Department of Surgery, Mayo Clinic, Rochester, MN, USA.
概括
将袖子胃切除术转换为Roux-en-Y胃绕道术有效地消除了GERD的症状,并有助于减肥. 然而,针对GERD进行修改的患者与针对体重复发进行修改的患者相比,经历了较晚的重新手术.
科学领域:
- 腹部外科手术
- 胃肠病学
- 手术修复
背景情况:
- 从袖子胃切除术 (SG) 转换为Roux-en-Y胃绕道 (RYGB),用于胃食道反流症 (GERD) 和体重复发.
- 目前对SG和RYGB修订结果的研究存在矛盾,缺乏长期数据.
研究的目的:
- 在SG转换为RYGB后评估GERD症状的消失和额外的体重减轻.
- 为了比较针对GERD和体重复发的患者之间的结果.
主要方法:
- 对前性维护的多中心减肥手术数据的回顾性分析.
- 患者被分为GERD或体重复发指示组,以SG转换为RYGB.
- 分析的结果包括总体减肥,GERD解决,营养状况和并发症 (重新手术,再入院).
主要成果:
- 包括124名GERD患者和93名体重患者;体重组的初始BMI较高.
- 在修订后,两组的总体重减轻率相似 (GERD: 13%,体重: 16%).
- 超过75%的GERD患者在1年内出现症状消失;然而,GERD患者在4年内更晚重新手术 (14%对比4%).
结论:
- 将SG转换为RYGB对于GERD分辨率和进一步减重是有效的.
- 虽然GERD的修改是有效的,但与重复体重的修改相比,长期临床结果较差,特别是晚期重复手术的增加.
相关概念视频
Hospitals-II
Hospitals provide inpatient and outpatient services. Inpatient services provide care to patients that stay in the hospital for an extended period, ranging from days to months. Examples of inpatient services include intensive care units, hospital wards, or surgeries. Outpatient services provide care to patients who come to a hospital for a diagnostic or treatment but do not stay overnight —for example, diagnostic tests, surgical procedures, or health education.
Nurses that work in hospitals have...
Nurses that work in hospitals have...
Clinical Trials
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
Healthcare Agencies II
There are various healthcare agencies in the United States—some of which are managed by religious institutions and others by different government branches.
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources, and lay...
Parish nursing is a growing specialty nursing profession that focuses on holistic healthcare, health promotion, and illness prevention. It blends professional nursing practice with a health ministry, focusing on health and healing within the context of a Christian community. Parish nurses serve as health educators, referral sources, and lay...
Clinical Trials: Overview
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
Bioavailability Study Design: Healthy Subjects Versus Patients
Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
Investigation of Disease Outbreaks
Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...

