Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

9.6K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
9.6K
Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

9.5K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
9.5K
Olfaction01:25

Olfaction

45.1K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
45.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Decomposing neuroanatomical heterogeneity in depression: insights from an ENIGMA major depressive disorder working group study in 5146 individuals.

Translational psychiatry·2026
Same author

New neurons flatten social hierarchies.

Scientific reports·2026
Same author

Multidomain correlates of burnout: A population-based study using supervised machine learning.

Social psychiatry and psychiatric epidemiology·2026
Same author

How personality functioning shapes symptom development during and after treatment: A random intercept cross lagged panel analysis.

Comprehensive psychiatry·2026
Same author

"Locked in my body, caught up in my mind": Neural signatures of body image rumination in anorexia nervosa.

Brain research bulletin·2026
Same author

Menarche onset is an inflection point for mental health and brain development.

bioRxiv : the preprint server for biology·2026
Same journal

Microbiota-gut-brain axis in autism spectrum disorder: integrating brain structure, function, and transcriptomics.

Translational psychiatry·2026
Same journal

Neural mechanisms of fear memory precision and generalization: from auditory cortex to amygdala.

Translational psychiatry·2026
Same journal

Maraviroc attenuates inflammation-exacerbated cognitive and amyloid pathology in an early-stage Alzheimer's disease mouse model.

Translational psychiatry·2026
Same journal

High-order brain interactions during ketamine-induced state changes: A functional marker of response in late-life treatment-resistant depression?

Translational psychiatry·2026
Same journal

Immune-metabolic mediation of depression risk: Causal evidence from antibody and metabolite GWAS.

Translational psychiatry·2026
Same journal

DRD1 and DRD2 dopamine-sensitive neurons in the central amygdala respond differently to rewarding and aversive stimuli.

Translational psychiatry·2026
查看所有相关文章

相关实验视频

Updated: Sep 10, 2025

Author Spotlight: Exploring Olfactory Influences on Corticospinal Excitability - Insights and Innovations in Neurological Research
06:13

Author Spotlight: Exploring Olfactory Influences on Corticospinal Excitability - Insights and Innovations in Neurological Research

Published on: January 19, 2024

1.1K

通过嗅觉神经刺激调节突出网络连接

Carina Heller1,2,3,4,5,6, Maria Geisler7, Nicolas L Mayer8

  • 1Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany. carina.heller@uni-jena.de.

Translational psychiatry
|August 21, 2025
PubMed
概括
此摘要是机器生成的。

通过改变大脑连接, 刺激嗅觉粘膜可能有助于抑郁症. 这种针对突出网络和默认模式网络的新方法对未来的治疗有希望.

更多相关视频

A Free-breathing fMRI Method to Study Human Olfactory Function
10:42

A Free-breathing fMRI Method to Study Human Olfactory Function

Published on: July 30, 2017

9.7K
A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation
10:42

A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation

Published on: August 18, 2014

9.1K

相关实验视频

Last Updated: Sep 10, 2025

Author Spotlight: Exploring Olfactory Influences on Corticospinal Excitability - Insights and Innovations in Neurological Research
06:13

Author Spotlight: Exploring Olfactory Influences on Corticospinal Excitability - Insights and Innovations in Neurological Research

Published on: January 19, 2024

1.1K
A Free-breathing fMRI Method to Study Human Olfactory Function
10:42

A Free-breathing fMRI Method to Study Human Olfactory Function

Published on: July 30, 2017

9.7K
A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation
10:42

A Lateralized Odor Learning Model in Neonatal Rats for Dissecting Neural Circuitry Underpinning Memory Formation

Published on: August 18, 2014

9.1K

科学领域:

  • 神经科学
  • 精神病学
  • 大脑连接

背景情况:

  • 抑郁症与大脑突出网络 (SN) 和默认模式网络 (DMN) 的功能连接变化有关.
  • 在抑郁症中修改这些神经模式是临床上的挑战.
  • 嗅觉通路提供了直接通往神经元的途径,这表明有针对性的神经调节的潜力.

研究的目的:

  • 研究嗅觉神经刺激对大脑连接的作用.
  • 探索嗅觉刺激是否可以调节突出网络及其与默认模式网络的相互作用.

主要方法:

  • 使用一个随机的,盲目的,主体内设计.
  • 45名健康参与者接受了嗅觉或三神经刺激.
  • 使用休息状态功能磁共振成像 (fMRI) 来评估大脑连接.

主要成果:

  • 嗅觉刺激显著增加了神经元和皮质皮层 (嗅觉区域) 之间的功能连接.
  • 这种刺激增强了SN内部的连接性.
  • 嗅觉刺激削弱了SN和DMN之间的连接.

结论:

  • 嗅觉刺激显示有潜力调节与抑郁相关的大脑连接模式.
  • 这表明一种新的,极少侵入性的情绪障碍疗法.
  • 需要进一步的研究来证实抑郁症患者的疗效.