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Updated: Jun 20, 2026

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array
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Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array

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跨异质空间样本的细胞状态的多尺度和多背景可解释映射

Patrick C N Martin1, Wenqi Wang2, Hyobin Kim1

  • 1Department of Computational Biomedicine, Cedars-Sinai Medical Center, Hollywood, CA, USA.

Nature communications
|August 21, 2025
PubMed
概括

我们使用线性赋值问题 (LAP) 开发了一种新的细胞映射策略,用于比较空间数据,在不同数据集中超越现有的准确细胞分析方法.

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相关概念视频

Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...