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对儿童近视控制的重复低水平红光治疗与传统治疗:系统性审查和分析

Li Ping Liu¹, Yi Shan Hu¹, Huai Cheng Chen¹

¹Department of Ophthalmology, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, 322000, China.

Scientific reports

|August 21, 2025

概括

与传统治疗相比,重复的低水平红光 (RLRL) 治疗显著减缓了儿童近视的进展. 这种疗法还可以增强胸膜的厚度,

科学领域:

眼科眼科
生物医学工程
儿童医学

背景情况:

近视是一个日益严重的全球健康问题,
目前的近视控制策略包括脊髓瘤学和氨酸,但它们的有效性可能有所不同.
需要新的有效的干预措施来控制近视的进展.

研究的目的:

与标准近视治疗相比,评估重复低水平红光治疗 (RLRL) 的疗效.
以指导RLRL治疗近视控制的临床应用.
分析与RLRL治疗相关的轴长度和胆道厚度的变化.

主要方法:

一项涉及691名儿科参与者的七项研究 (包括RCT,队列研究和非随机对照试验) 的元分析.
在主要数据库 (PubMed,Embase,Web of Science,Cochrane Library) 进行文献搜索,直到2024年12月.
使用加权平均差异 (WMDs) 的统计分析,使用95%的置信区间 (CI),元回归,子组分析和出版偏差测试.

主要成果:

与对照组相比,RLRL治疗显示轴长度进展明显较低 (WMD=- 0. 24 mm,P< 0. 001).
与单独治疗相比,辅助RLRL治疗对控制轴长度增长的效果更大.
RLRL治疗导致冠状腺厚度显著增加,超过了脊髓瘤学和0. 01%的类药物 (WMD=30. 79μm,P<0. 05).
在包括的研究中没有报告严重的不良反应.

结论:

与目前的标准治疗相比,RLRL治疗在减缓近视的进展方面似乎更有效.
随着干预时间的延长,RLRL治疗的益处会增加.
需要进行更多精心设计的临床试验,并延长随访期,以证实RLRL治疗对近视的长期临床价值.

关键词:

亚特罗平轴的长度综合分析脊椎病学重复的低级红灯

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