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Updated: Sep 10, 2025

Analysis of Cell Cycle Position in Mammalian Cells
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BRCA1和BRCA2基因表达:p53-和细胞周期依赖的抑制需要RB和DREAM

Marianne Quaas1,2, Robin Kohler1, Lukas Nöltner1

  • 1Molecular Oncology, Faculty of Medicine, University of Leipzig, Leipzig, Germany.

Cell death and differentiation
|August 21, 2025
PubMed
概括

在细胞循环停止和DNA损伤过程中,对DNA修复至关重要的BRCA1和BRCA2基因表达被p53和抑制器复合体抑制. 这种转移促进易于错误的修复,防止恶性转变.

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