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Updated: Sep 10, 2025

Radiolabeling and Quantification of Cellular Levels of Phosphoinositides by High Performance Liquid Chromatography-coupled Flow Scintillation
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通过依赖于Sac1的PI(4) P和胆固醇对Golgi- V- ATPase进行控制

Xin Zhou1,2, Miesje M van der Stoel1,2, Shreyas Kaptan3

  • 1Stem Cells and Metabolism Research Program and Department of Anatomy, Faculty of Medicine, University of Helsinki, Helsinki, Finland.

Nature communications
|August 21, 2025
PubMed
概括

通过禁用V-ATPase,Sac1酸酶的损失迅速破坏了跨戈尔吉网络 (TGN). 这导致戈尔吉分裂和蛋白质处理缺陷,影响细胞活力.

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