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在塔巴里群体中未诊断的3期慢性病的患病率:基于人群的研究
Mahmood Moosazadeh1, Farhad Gholami2, Pedram Ebrahimnejad3
1Gastrointestinal Cancer Research Center, Non-Communicable Diseases Research Institute, Mazandaran University of Medical Sciences, Mazandaran, Iran.
BMC nephrology
|August 21, 2025
概括
在一项大型人群研究中发现了未诊断的3期慢性病 (CKD) 的高患病率. 城市居民和没有高血压,糖尿病或心血管疾病的人更有可能患有未确诊的CKD.
科学领域:
- 肝脏病学
- 流行病学
- 公共卫生
背景情况:
- 慢性病是一个全球性的健康问题.
- 早期的CKD通常没有症状,导致诊断延迟.
- 调查未诊断的CKD对于公共卫生干预至关重要.
研究的目的:
- 在大量人群中确定未被诊断的3期CKD的流行率.
- 确定与未诊断的3阶段CKD相关的因素.
主要方法:
- 塔巴里队列研究 (TCS) 数据的横截面分析 (2015-2017).
- 包括35至70岁的10,255名成年人.
- 基于使用MDRD方程估计的球过率 (eGFR) 诊断CKD;第3阶段CKD定义为30 ≤eGFR <60 mL/min/1.73 m2.
- 用物流回归分析来确定预测因素.
主要成果:
- 25. 6% 的参与者患有第三阶段的CKD.
- 98. 1% 患有3 期慢性脏病的人不知道自己的病情.
- 在山区居民和高血压,糖尿病或心血管疾病患者中,未被诊断的3期CKD的风险较低.
结论:
- 很大一部分人患有未确诊的3期CKD.
- 城市居民和缺乏并发症 (高血压,糖尿病,心血管疾病) 与未诊断的3期CKD的更高患病率有关.
- 这些发现凸显了针对性查和宣传计划的必要性.
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