针对没有光环的偏头痛的预防效果:随机化,虚假控制的临床试验
Mingsheng Sun1,2, Chaorong Xie1, Yanan Wang1,3
1The Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Journal of evidence-based medicine
|August 21, 2025
概括
手动穿透针 (MPA) 与假针 (NPA) 相比,显示出更好的长期偏头痛缓解和生活质量改善. 选择针点是关键,但针方法决定了偏头痛治疗的持续临床益处.
科学领域:
- 神经学
- 综合医学
- 临床试验
背景情况:
- 针是一种有效的偏头痛治疗方法.
- 不同针方法在相同针点的长期疗效并未得到充分证实.
- 本研究将手动穿透针 (MPA) 与假冒非穿透针 (NPA) 进行偏头痛预防.
研究的目的:
- 在偏头痛患者中研究MPA与NPA在相同针点的预防作用.
- 为了比较不同针治疗偏头痛的长期疗效.
主要方法:
- 一个多中心,单盲随机对照试验,涉及192名没有光环的偏头痛患者.
- 参与者接受了12次MPA或NPA治疗.
- 主要结局:16周偏头痛发作频率的变化;次要结局包括响应率和疼痛强度.
主要成果:
- 与16周的NPA相比,MPA的响应率 (17. 2%的差异,p=0. 007) 和疼痛减轻率 (MD=- 0. 6, p=0. 003) 较高.
- 在治疗后,MPA 持续改善了偏头痛症状和生活质量.
- 在5. 1%的MPA参与者中报告了不良事件.
结论:
- 虽然MPA和NPA都有相似的预防作用,但MPA可以持续缓解症状并提高生活质量.
- 针点的选择对治疗潜力至关重要.
- 针方法对偏头痛的治疗具有显著的长期临床效益.
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