关于怀孕风险因素与分娩结果之间的相关性研究
1Liaoning Maternal and Child Health Hospital, Shenyang, Liaoning, China.
Scientific reports
|August 21, 2025
概括
孕产妇体重不足和孕期体重增加不足会增加低出生体重和孕期体重小的婴儿的风险. 另一方面, 孕妇肥胖和过度体重增加与巨和早产有关.
科学领域:
- 产科和妇科
- 公共卫生
- 生产周边流行病学
背景情况:
- 低出生体重 (LBW) 和早产 (PTB) 等不良出生结果是全球重要的健康问题.
- 母体质量指数 (BMI) 和孕期体重增加 (GWG) 是已知的危险因素,但它们与中国的代谢和社会人口因素的相互作用需要研究.
研究的目的:
- 在大量中国人群中调查孕前BMI,GWG和其他因素与不良分娩结果之间的关联.
- 确定中国东北部城市化不利出生结果的关键可修改决定因素.
主要方法:
- 2012年至2018年在中国宁的1,026,294例单子怀孕的前性队列研究.
- 使用多变量逻辑回归模型来计算调整后的风险比率 (RR) 和95%的置信区间 (CI).
- 评估了产前暴露与结果之间的关联,包括LBW,巨,SGA,LGA和PTB.
主要成果:
- 在怀孕前体重不足和GWG不足与LBW和SGA有很强的关联.
- 在怀孕前的肥胖和过度的GWG与宏观症的风险增加有关.
- 妊娠前的肥胖,辅助生殖受孕和早期高血糖与PTB有关.
- 确定了特定区域的风险值,宁的超重/肥胖和巨眼病率高于全国平均水平.
结论:
- 孕前母亲的BMI和GWG是不良分娩结果的关键,可改变的决定因素.
- 高血压疾病和代谢标志物也起着重要作用.
- 这些发现突显出需要在中国东北部进行有针对性的GWG监测和代谢查.
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