相关实验视频

Updated: Sep 10, 2025

Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype
14:51

Pooled shRNA Library Screening to Identify Factors that Modulate a Drug Resistance Phenotype

Published on: June 17, 2022

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以p16INK4a为媒介的细胞衰老作为FLT3-ITD驱动的急性髓性白血病的治疗策略

Jiarui Zheng1,2, Linlin Jin1,2, Yunlong Chen1,2

  • 1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300020, China.

Leukemia
|August 21, 2025
PubMed
概括

在急性髓性白血病 (AML) 中FLT3- ITD突变抑制瘤抑制剂p16INK4a,导致衰老逃避和更糟糕的患者结果. 针对这种途径为FLT3-ITDAML提供了新的治疗策略.

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A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence13:59

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence

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