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对MCI成年人不同运动方式的有效性进行比较:网络元分析

Changjiang Qiu^1,2, Jiaxin Han^1,2, Yao Xie³

¹Hunan University of Chinese Medicine, Changsha, China.

Brain and behavior

|August 22, 2025

概括

组合训练是改善轻度认知障碍 (MCI) 患者认知功能的最有效方法. 这种方法显著提高了MoCA和MMSE测试的分数,可能会减缓疾病的进展.

科学领域:

神经学
老年学
运动科学

背景情况:

轻度认知障碍 (MCI) 是阿尔茨海默病 (AD) 的临床前阶段.
与普通老年人群 (1% - 2%) 相比,MCI患者每年发展为痴呆症的比率显著高 (10% - 15%).

研究的目的:

评估不同运动方式在患有MCI的成年人中改善认知功能的有效性.
进行网络元分析 (NMA),比较MCI的各种运动干预措施.

主要方法:

对相关的随机对照试验 (RCT) 在 Embase,PubMed,Cochrane Library 和 Web of Science 进行了全面的文献搜索.
数据提取和质量评估由两位审查员独立进行.
使用RevMan 5. 4, Stata 15和R 4. 4.1进行了统计分析.

主要成果:

网络分析包括35项涉及2717名参与者的研究.
综合训练 (CT) 在MCI患者的蒙特利尔认知评估 (MoCA) 和迷你精神状态检查 (MMSE) 得分中显示出最大的改善.
阻力训练和感官运动训练被确定为提高MMSE和MoCA分数的下一个最有效的干预措施.

结论:

组合训练是改善MCI患者MoCA和MMSE分数的最佳运动干预措施.
运动,特别是组合训练,可以缓解MCI的进展.
需要进一步的大规模双盲临床试验来验证这些发现.

关键词:

美国认知能力多组件运动模式网络元分析

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