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Updated: Sep 10, 2025

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异形选择性Akt3降解剂的设计,合成和生物评估

Ye-Bin Wu1, Qiu-Hua Zhou1, Xiao-Jun Ji1

  • 1Innovation Department of the Research Institute, Nanjing Chia-Tai Tianqing Pharmaceutical Co., Ltd., Nanjing 210046, P. R. China.

Journal of medicinal chemistry
|August 22, 2025
PubMed
概括

研究人员开发了一种新型化合物,可选择性降解与癌症相关的Akt3激酶. 这种有针对性的方法旨在通过专门消除Akt3而改善癌症治疗,而不会影响相关蛋白质.

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Structure-Activity Relationships and Drug Design01:28

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