饮食营养模式与刺激性肠综合征的关系:多中心病例对照研究
E Fazeli Moghadam1, M Samadi2, S Mohammadi1
1Nutritional Health Research Center, Nutrition, School of Health and Nutrition Lorestan University of Medical Sciences Khorramabad Iran.
Food science & nutrition
|August 22, 2025
概括
富含抗氧化剂和纤维的饮食模式与刺激性肠综合征 (IBS) 的几率较低有关. 这项研究强调营养摄入模式对于治疗IBS至关重要.
科学领域:
- 营养科学
- 胃肠病学
- 公共卫生
背景情况:
- 刺激性肠综合征 (IBS) 是一种常见的胃肠疾病,已知与饮食有关.
- 然而,特定的基于营养的饮食模式及其与IBS的关联仍未得到充分研究.
- 研究营养摄入模式为了解IBS病因提供了一种新方法.
研究的目的:
- 检查基于营养的饮食模式与IBS的患病率之间的关系.
- 在成年人群中确定与IBS发病率降低相关的特定营养模式.
- 探索抗氧化剂,纤维和糖摄入在IBS风险中的作用.
主要方法:
- 一项多中心病例控制研究,涉及317名IBS患者和601名健康对照患者 (2021-2023年).
- 使用168项食物频率问卷 (FFQ) 评估饮食习惯.
- 确定了营养模式,并使用后勤回归来分析与IBS的关联,并调整了混因素.
主要成果:
- 两种不同的营养模式与IBS几率较低显著相关:模式I (含有高抗氧化剂,如β-胡卜素,维生素A,C,E) 和模式II (富含纤维,葡萄糖,果糖,麦芽糖).
- 对I模式的较高坚持率显示为0.75 (95%CI为0.62-0.92,p=0.00).
- 对模式II的较高坚持表明OR为0. 52 (95% CI为0. 42- 0. 64, p=0. 00).
- 第三种模式,高糖和咖啡因,与IBS没有显著的关联 (OR 0. 95,95% CI 0. 80-1.12,p>0. 05).
结论:
- 富含抗氧化剂和纤维的营养模式与刺激性肠综合征的风险降低有关.
- 增加抗氧化剂丰富的食物和纤维的饮食干预措施可能有利于IBS的预防.
- 需要进一步的研究来阐明这些营养模式与IBS的联系机制.
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