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Updated: Sep 10, 2025

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
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蛋白质学驱动的精准医学的未来时代

Ying Jiang1, Jian Wang1, Aihua Sun1

  • 1State Key Laboratory of Medical Proteomics, Research Unit of Proteomics Driven Cancer Precision Medicine (Chinese Academy of Medical Sciences), Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Academy of Military Medical Sciences, Beijing 102206, China.

National science review
|August 22, 2025
PubMed
概括

蛋白质组学正在彻底改变精确医学, 蛋白质组学的进步使得更好的疾病预测,早期诊断和个性化治疗能够改善医疗保健结果.

关键词:
这是一种药物.翻译后的修改精准医学蛋白质与蛋白质的相互作用蛋白质组学空间蛋白质组

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相关概念视频

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
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