人类大脑皮层的时间变化的协同/冗余主导
Maria Pope1,2, Thomas F Varley3, Maria Grazia Puxeddu4
1School of Informatics, Computing & Engineering, Indiana University, Bloomington, IN, United States of America.
概括
大脑的相互作用主要是冗余的,但在功能系统的解体过程中会出现协同作用. 这些复杂的动态显示了多种交互尺度的结构性时间模式,
科学领域:
- 神经科学
- 信息理论
- 大脑成像
背景情况:
- 高级互动对于大脑功能至关重要.
- 互动可以是协同主导或冗余主导.
- 这些相互作用的动态结构在很大程度上是未知的.
研究的目的:
- 在休息期间分析fMRI BOLD信号中的协同效应和冗余的动态结构.
- 在不同尺度上调查互动的时刻主导性.
- 了解功能系统动态如何与交互类型相关.
主要方法:
- 应用到fMRI BOLD信号的多变量信息理论工具.
- 在休息状态下对95个无关体进行分析.
- 对不同大脑区域子集大小的相互作用动态的检查.
主要成果:
- 整个大脑主要由冗余主导,有些个体没有显示整个大脑的协同作用.
- 由冗余主导的小脑区域子集表现出复杂的动态和峰值协同/冗余.
- 协同作用发生在功能系统中的瞬间解体过程中,这种模式也在较大的子集中见到.
结论:
- 大脑相互作用在多个尺度上表现出高度结构化的时间动态.
- 交互节点的变化是平稳的,重复的,这突显了时间局部化措施的相关性.
- 了解这些动态对于未来的行为和认知研究至关重要.
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