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口腔粘膜黑色素瘤的生存率和预后因素:一个元分析
Alberto Rodriguez-Archilla1,2, Pablo Valverde-Martinez1
1Department of Stomatology, Oral Medicine Unit, Faculty of Dentistry, University of Granada, Granada, Spain.
Journal of dental research, dental clinics, dental prospects
|August 22, 2025
概括
口腔黑色素瘤的存活率很低,随着时间的推移显著下降. 没有的高颜色瘤的预后更好, 而的低颜色瘤的预后更糟.
科学领域:
- 癌症学
- 皮肤病学
- 口腔医学
背景情况:
- 由于口腔血管和淋巴排水,口腔黑色素瘤通常会早期转移.
- 延迟诊断导致口腔黑色素瘤患者的预后较差.
研究的目的:
- 确定口腔黑色素瘤在不同时间段的存活率.
- 确定影响口腔黑色素瘤生存的预后因素.
主要方法:
- 在PubMed,Web of Science和Scopus进行了系统的文献搜索.
- 使用通用逆方差方法对聚合比例和Mantle- Haenszel方法对赔率进行了元分析.
- 包括3767名口腔黑色素瘤患者的38项研究.
主要成果:
- 整体存活率从2年后的58%下降到5年后的29%.
- 没有的口腔黑色素瘤显示最好的5年存活率.
- 瘤的位置和性别对口腔黑色素瘤的存活率没有显著影响.
结论:
- 口腔黑色素瘤与低生存率有关.
- 和颜色差的瘤是口腔黑色素瘤的最坏预后.
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