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Updated: Sep 10, 2025

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术后认知功能障碍是微质炎症记忆的疾病吗? 从代谢压力到表观遗传锁定状态的转变模型

Xiangyu Wu1,2, Tingye He1,2, Fei He1,2

  • 1Department of Anesthesiology, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China.

Frontiers in molecular neuroscience
|August 22, 2025
PubMed
概括

术后认知功能障碍 (POCD) 源于微质认同的稳定转变, 而不是短暂的炎症. 这种"炎症记忆回路"使质细胞处于神经毒性状态,

关键词:
表观遗传重编程微质炎症记忆线粒体功能障碍神经免疫可塑性术后认知功能障碍

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