中国内脏脂肪指数与糖尿病患者心力衰竭之间的关联
Shiwei Kang1, Shuohua Chen2, Zuxu Lin1
1School of Public Health, North China University of Science and Technology, Tangshan, China.
Diabetes, obesity & metabolism
|August 22, 2025
概括
中国内脏脂肪指数 (CVAI) 与糖尿病患者心力衰竭 (HF) 的风险较高有关. 这一指数对于在老年人中识别高风险特别有用.
科学领域:
- 心脏病学
- 内分泌学
- 公共卫生
背景情况:
- 糖尿病是心血管疾病,包括心力衰竭 (HF) 的重要危险因素.
- 腹部脂肪在糖尿病患者心血管并发症的发病过程中起着至关重要的作用.
- 对于糖尿病患者群体,准确的风险分层对于有效的预防和管理至关重要.
研究的目的:
- 研究中国内脏脂肪指数 (CVAI) 与糖尿病患者心力衰竭 (HF) 风险之间的关联.
- 将CVAI的预测能力与其他已确定的HF风险肥胖指标进行比较.
主要方法:
- 一项前性队列研究 (Kailuan研究) 包括从2006年至2022年跟踪的12243名糖尿病患者.
- 参与者根据他们的CVAI值被分为四分之一.
- 使用卡普兰 - 梅尔分析,考克斯回归和ROC分析来评估CVAI和HF发病率之间的关系及其预测准确性.
主要成果:
- 在15年的中位数中,发现了861例新的HF病例.
- 在较高的CVAI四分位数中,HF发病率呈显著上升趋势 (p < 0. 05).
- 较高的CVAI水平独立地与HF风险增加有关,在60岁及以上的患者中观察到显著的相互作用.
结论:
- 中国内脏脂肪指数 (CVAI) 是糖尿病患者心力衰竭风险的独立预测指标.
- 与其他肥胖指数相比,CVAI的预测准确度更高.
- 对于与内脏脂肪相关的HF风险分层来说,CVAI特别有价值,特别是在老年糖尿病患者中.
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