具有Gerbode缺陷和DRESS综合征的传染性内心炎:一个罕见病例报告
Corina Ureche1,2, Diana Lavinia Moldovan3, Ionel Vița3
1Second Internal Medical Department, George Emil Palade University of Medicine, Pharmacy, Science and Technology, 540142 Târgu Mureș, Romania.
Reports (MDPI)
|August 22, 2025
概括
患有罕见的Gerbode缺陷的患者的传染性内心炎 (IE) 由DRESS综合征,一种严重的药物反应而复杂化. 及时识别和治疗这种罕见的并发症对于患者的结果至关重要.
科学领域:
- 心脏病学
- 传染性疾病
- 临床药理学
背景情况:
- 感染性内心炎 (IE) 的发病率正在上升,通常由金黄色葡萄球菌引起.
- 格博德缺陷是一种罕见的先天性心脏异常,与IE不常见.
- 药物反应与乙素和系统性症状 (DRESS) 综合征是对药物的严重过敏反应,包括用于IE的抗生素.
研究的目的:
- 报告第一个经证实患有Gerbode缺陷的患者的IE病例.
- 描述这位病人的DRESS综合征并发症.
- 强调需要警和改进的管理策略.
主要方法:
- 一个65岁的老妇人的病例介绍.
- 通过血液培养和心声学证实了诊断.
- 治疗包括抗生素,皮质类固醇和抗生素修饰.
主要成果:
- 这位患者出现了心脏器官,三门和Gerbode缺陷的IE.
- 在治疗中出现了DRESS综合征,其特征是皮疹,阴,多器官受影响.
- 随着迅速的治疗,获得了临床改善.
结论:
- 特别是在罕见的心脏异常的情况下,在长期的IE抗生素治疗中识别DRESS综合征的重要性.
- 这强调了对这种可能致命的并发症的最佳诊断和治疗指南的需要.
- 强调多学科护理在处理复杂的IE病例中的关键作用.
相关概念视频
Endocarditis II: Clinical Features of Infective Endocarditis
25
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
25
Endocarditis I: Introduction
26
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
26
Endocarditis III: Medical Management
17
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
17
Endocarditis IV: Nursing Management
27
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
27
Rheumatic Heart Disease I: Introduction
39
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
39
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
57
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
57


