减补性肝硬化患者的患者健康问卷-9的差异性项目的功能
Nneka N Ufere1, Chengbo Zeng2, Daniel Shalev3
1Liver Center, Gastrointestinal Division, Massachusetts General Hospital, Boston, MA, USA.
Clinical and translational gastroenterology
|August 22, 2025
概括
与初级护理相比,抑郁症症状的表现在非补偿性肝硬化患者中不同. 在DC患者中,睡眠问题和低能量的特定体征更为常见,这表明调整了查值.
科学领域:
- 医学研究
- 临床心理学
- 肝病学
背景情况:
- 广泛使用的抑郁症查工具包括患者健康问卷-9 (PHQ-9).
- 在不同患者群体中,抑郁症的症状表现可能有所不同.
- 不补偿性肝硬化 (DC) 是一种严重的肝病,可能会影响精神健康症状.
研究的目的:
- 检查使用PHQ-9的非补偿性肝硬化 (DC) 患者和初级保健患者之间是否存在抑郁症症状表现的差异.
- 评估差异物件功能 (DIF) 对DC患者PHQ-9分数的影响.
主要方法:
- 对比了218名DC患者 (Child- Pugh类B/ C) 和436名初级护理门诊患者的PHQ-9抑郁查工具数据.
- 两个群体的阳性抑郁查率 (PHQ-9截止分数为10).
- 使用项目响应理论 (IRT) 评估PHQ-9项目的差异性项目功能 (DIF),并比较DIF调整和未调整的分数.
主要成果:
- 抑郁症查率在DC患者中为39%,在初级保健患者中为30%.
- 三个PHQ-9体质项目 (睡眠问题,低能耗,精神动作/延迟) 呈现出显著的DIF,更多的是DC患者.
- 根据DIF调整的分数表明,DC患者可能需要一个更高的查值 (PHQ-9分数为11).
结论:
- 在使用PHQ-9时,DC和初级保健患者之间存在显著的抑郁症状表现差异.
- 这些发现强调了进一步研究抑郁症查工具的诊断准确性和DC患者抑郁症的具体现象学的必要性.
相关概念视频
01:23Assessment of the Cardiovascular System I: Subjective Data
467
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
467
01:25Ultrasound II: Endoscopic Ultrasound and FibroScan
198
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
Endoscopic Ultrasound (EUS):
198
01:29Assessment of the Gastrointestinal System II: Health Perception Pattern
162
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
Health Perception Patterns
Health perception patterns offer valuable insights into a patient's lifestyle habits and how they may impact their GI health. These patterns include:
162