开发一个基于共识的核心结果集,用于治疗后的和伴随性抑郁症或焦虑症的成年人:Delphi和ICF指导的协议
Yan Wang1, Zaibang Feng2, Zhiyue Guo3
1Department of Neurology, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.
PloS one
|August 22, 2025
概括
这项研究为患有和并发性抑郁症或焦虑症的成年人制定了核心结局 (COS). 这种标准化的方法将改善对复杂的双诊断群体的结果测量和个性化护理.
科学领域:
- 神经科学
- 精神病学
- 公共卫生
背景情况:
- 在成年人中,经常与抑郁或焦虑并发 (高达50%).
- 现有的核心结果集 (COS) 缺乏对的精神健康并发症的关注.
- 需要从生物心理社会角度来评估这一群体的结果.
研究的目的:
- 开发一种标准化的COS来评估患有和并发性抑郁症或焦虑症的成年人的治疗后恢复.
- 通过使用国际功能,残疾和健康分类 (ICF) 框架,确保全面的生物心理社会视角.
- 提高跨研究的可比性,并为这个服务不足的群体提供个性化护理.
主要方法:
- 对伴随性抑郁/焦虑的成年患者的结果进行系统审查 (PubMed,Embase,Cochrane).
- 将已识别的结果映射到ICF领域 (身体功能,活动,参与).
- 与60名国际利益相关者 (神经科医生,精神科医生,心理学家,患者,护理人员) 进行三轮德尔菲调查,以达成共识.
主要成果:
- 系统审查将确定相关结果,包括控制,情绪稳定,认知功能,社会重返,以及与自杀相关的结果.
- 将结果系统地映射到ICF框架中.
- 德尔菲调查将建立对COS至关重要的结果的共识.
结论:
- 这种新型的COS将解决患有和精神疾病的成年人治疗结果的关键差距.
- 这种以ICF为指导,包容患者的方法确保了全球相关性,并补充了现有的COS.
- 开发的COS将加强研究,临床实践和个性化护理,并计划在未来进行验证.
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