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Updated: Sep 10, 2025

An Integrated Workflow of Identification and Quantification on FDR Control-Based Untargeted Metabolome
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An Integrated Workflow of Identification and Quantification on FDR Control-Based Untargeted Metabolome

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具有FDR控制的新和强大的特征选择方法用于全omics关联分析

Zhibo Chen1, Zi-Tong Lu1, Xue-Ting Song1

  • 1School of Statistics and Mathematics, Zhongnan University of Economics and Law, Wuhan, Hubei, People's Republic of China.

PloS one
|August 22, 2025
PubMed
概括

这项研究引入了一种新的特征选择方法,用于全欧米学协会分析. 它准确地识别复杂的高维数据集中的风险特征,同时控制错误发现率 (FDR).

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相关概念视频

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
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