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Updated: Sep 10, 2025

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
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Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway

Published on: August 23, 2024

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强大的AMPK抑制剂BAY-3827的机制和细胞作用

Conchita Fraguas Bringas1, Mohd Syed Ahangar2, Joyceline Cuenco1

  • 1Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark.

Science advances
|August 22, 2025
PubMed
概括

新研究详细介绍了新型AMPK抑制剂BAY-3827,揭示了其独特的作用机制和细胞选择性. 这一发现为与氨酸5'-单酸 (AMP) 激活蛋白激酶 (AMPK) 信号相关的疾病提供了更好的治疗潜力.

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