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Updated: Sep 10, 2025

Using Cholesky Decomposition to Explore Individual Differences in Longitudinal Relations between Reading Skills
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Using Cholesky Decomposition to Explore Individual Differences in Longitudinal Relations between Reading Skills

Published on: September 17, 2019

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在分析二进制特征时检测隐藏的相互作用效应

Ziang Zhang1,2, Jerald F Lawless3, Andrew D Paterson4,5

  • 1Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America.

PLoS genetics
|August 22, 2025
PubMed
概括

这项研究引入了一种全基因组关联研究 (GWAS) 的新方法,用于检测二进制特征的基因环境相互作用. 这种方法简化了复杂基因相互作用的测试,提高了与疾病相关的SNP和基因的发现能力.

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