尼日利亚里弗斯州糖尿病足中缺乏维生素D水平的风险
U D Batubo1, B Oyan1, U Umoren2
1Department of Internal Medicine, Rivers State University Teaching Hospital, Port Harcourt, Rivers State, Nigeria
West African journal of medicine
|August 22, 2025
概括
较低的维生素D水平与2型糖尿病患者的糖尿病足 (DFU) 有关. 解决维生素D缺乏症可能会改善DFU的结果.
科学领域:
- 内分泌学
- 代谢疾病
- 血管健康
背景情况:
- 全球糖尿病率上升,特别是在发展中国家,增加了糖尿病足等并发症.
- 在患有慢性血管疾病的2型糖尿病 (T2DM) 患者中,低维他命D常见.
- 这项研究研究了维生素D水平与T2DM患者足部的发生之间的关系.
研究的目的:
- 确定血清维生素D水平与T2DM患者糖尿病足的存在之间的关联.
- 为了比较T2DM患者的维生素D水平.
- 探索维生素D缺乏与糖尿病足的严重性之间的相关性.
主要方法:
- 一项病例对照研究涉及88名患有DFU的T2DM患者和88名没有DFU的T2DM患者.
- 使用标准血液检测测量血清维生素D水平.
- 统计分析包括独立的t测试,皮尔森相关性和线性回归来评估关联.
主要成果:
- 与对照组 (36. 2 ng/ ml) 相比,DFU患者的血清维生素D水平显著降低 (19. 6 ng/ ml).
- 84. 1% 患有足部的患者缺乏/ 缺乏维生素D,而没有足部的患者为 29. 5%.
- 缺维生素D患者患维生素D不足的可能性是12. 6倍; 缺维生素D严重程度与维生素D水平较低相关 (p=0.0001).
结论:
- 低血清维生素D水平与T2DM患者的糖尿病足有很强的联系.
- 查和纠正维生素D缺乏症可能是管理DFU的有益策略.
- 需要对维生素D补充剂的预防和治疗进行进一步的研究.
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