用apigenin补充饮食可以改善患有死肠炎的 brojlers的肠道损伤
Yiming Li1, Qiyuan Zhao1, Qi Zhang1
1College of Animal Science and Technology, Guangxi Key Laboratory of Animal Breeding, Disease Control and Prevention, Guangxi grass station, Guangxi University, Nanning, 530004, Guangxi, China.
Poultry science
|August 22, 2025
概括
在患有死肠炎 (NE) 的 brojlers 中,饮食补充apigenin改善了生长和肠道健康. 增强了抗氧化活性和调节了免疫反应,有效地减轻了NE引起的肠损伤.
科学领域:
- 禽类科学
- 动物营养
- 免疫学
背景情况:
- 死亡性肠炎 (NE) 是 brojlers的一个重要疾病,造成了巨大的经济损失.
- 它对生长性能,肠道屏障完整性和免疫功能产生负面影响.
- 饮食干预对于管理NE和改善肉健康至关重要.
研究的目的:
- 调查饮食中的阿皮根因对 NE brojlers 的生长性能,肠道屏障完整性和免疫反应的影响.
- 评估apigenin减轻NE诱导的病理变化的潜力.
- 为了确定肉健康的最佳补充水平.
主要方法:
- 共有144只肉被分为六组,其中NE是由Eimeria maxima和Clostridium perfringens引起的.
- 从化后的第24天到第28天进行了食补充剂 (500 mg/ kg).
- 评估了生长性能,肠道形态,抗氧化能力和免疫细胞因子水平.
主要成果:
- 它显著降低了平均每日增益 (ADG) 和料转换率 (FCR).
- 抗氧化能力受损,肠道透性增加,细胞因子 (IL- 1β,IL- 6,TNF- α,IL- 10) 变化.
- 原蛋白补充剂 (500 mg/ kg) 有效地改善了ADG和FCR,增强了抗氧化活性,恢复了肠道形态,并调节了免疫反应.
结论:
- 补充食原蛋白是一种有前途的策略,可以缓解肉中NE引起的负面影响.
- 增强抗氧化能力和调节免疫反应,从而改善肠道屏障功能.
- 进一步的研究可以探索apigenin在其他家禽疾病中的作用和最佳剂量.
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