甲状腺眼病中的光学连贯性断层扫描血管学测量:系统性审查和元分析
Mehrdad Mozafar1, Sepehr Fekrazad2, Mobina Amanollahi1
1School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Survey of ophthalmology
|August 22, 2025
概括
甲状腺眼病 (TED) 显著影响视网膜血管,特别是在活跃阶段. 光学连贯断层扫描血管图 (OCTA) 显示活跃TED患者血管密度降低和血管区域扩大.
科学领域:
- 眼科 眼科
- 内分泌学
- 医学成像
背景情况:
- 甲状腺眼病 (TED) 是格雷夫斯病的一个眼部并发症.
- 通过自身免疫和机械过程影响视网膜血管.
- 评估TED中的微血管变化对于了解疾病进展至关重要.
研究的目的:
- 在TED患者中使用光学连贯断层扫描 (OCTA) 评估视网膜微血管变化.
- 为了比较活跃的TED,不活跃的TED和健康的对照组.
- 强调OCTA在诊断和监测TED中的作用.
主要方法:
- 在PubMed,Scopus和Web of Sciences的系统文献搜索中搜索TED的OCTA研究.
- 使用相同OCTA装置的研究中的OCTA参数的元分析.
- 包含了15项研究,包括771个TED眼睛 (活跃和非活跃阶段).
主要成果:
- 与不活跃的TED和对照组相比,表面和深层毛细血管的血管密度 (VD) 显著降低.
- 在活跃的TED中,
- 在活跃的TED中,辐射周毛细血管静脉疾病减少.
结论:
- OCTA是帮助TED诊断的一个有价值的非侵入性工具.
- OCTA可以在TED中帮助监测疾病的进展.
- 未来的研究需要更大,更多样化的样本来证实TED对视网膜性性疾病的发现.
相关概念视频
Open Angle Glaucoma: Treatment
561
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
561
Imaging Studies III: Computed Tomography
50
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
50
Glaucoma: Overview
749
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
749
Angle Closure Glaucoma: Treatment
674
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
674
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
119
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
119
Imaging Studies for Cardiovascular System V: CT
66
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
66


