在循环死亡的捐赠者之后,Capnometry可以预测从不受控制的捐赠获得的的生存能力.
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在PubMed上查看摘要
概括
此摘要是机器生成的。在医院抵达时进行透测量有助于识别循环死亡 (uDCD) 后有效的无控制捐赠者. 年龄较小和机械胸部压缩等因素也可以预测捐赠者的移植能力.
科学领域
- 移植免疫学
- 器官捐献科学
- 危急护理医学
背景情况
- 在循环死亡 (uDCD) 后的无控制捐赠提供了很好的长期移植存活率.
- 大部分的UDCD移植不适合移植.
- 在心肺复苏 (CPR) 期间的测量反映了组织代谢和器官 perfusion.
研究的目的
- 确定潜在的UDCD捐赠者的度值是否可以区分可行的和无效的捐赠者.
- 确定与捐赠者的生存能力相关的医院前变量.
主要方法
- 在两个移植中心进行回顾性研究 (2018-2023年).
- 包括没有成功的医院外心肺复苏的患者,符合UDCD标准.
- 分析了心肺复苏开始,中期和入院时间,以及其他医院前的变量.
主要成果
- 69个潜在的UDCD捐赠者:26个有效 (37.7%) 和43个无效 (62.3%).
- 在有效捐赠者 (26 mmHg) 与无效捐赠者 (15 mmHg;P<0.004) 抵达医院时的较高度值.
- 转移度的最佳切断值为17 mmHg. 机械胸部压缩,短暂的脉冲回归,较年轻的捐赠者年龄,以及更高的到达度独立预测了生存能力.
结论
- 在抵达医院时进行透测量是识别可行的UDCD捐赠者的一个有价值的工具.
- 较年轻的捐赠者年龄,机械胸部压缩和短暂的脉回归是捐赠者生存能力的重要预测因素.
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