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在循环死亡的捐赠者之后,Capnometry可以预测从不受控制的捐赠获得的的生存能力

Carlos Rubio-Chacón¹, Alonso Mateos-Rodríguez², Fernando Neria³

¹Emergency Medical Service of the Community of Madrid, SUMMA 112, Madrid, Spain.

|August 22, 2025

概括

在医院抵达时进行透测量有助于识别循环死亡 (uDCD) 后有效的无控制捐赠者. 年龄较小和机械胸部压缩等因素也可以预测捐赠者的移植能力.

科学领域:

移植免疫学
器官捐献科学
危急护理医学

背景情况:

在循环死亡 (uDCD) 后的无控制捐赠提供了很好的长期移植存活率.
大部分的UDCD移植不适合移植.
在心肺复苏 (CPR) 期间的测量反映了组织代谢和器官 perfusion.

研究的目的:

确定潜在的UDCD捐赠者的度值是否可以区分可行的和无效的捐赠者.
确定与捐赠者的生存能力相关的医院前变量.

主要方法:

在两个移植中心进行回顾性研究 (2018-2023年).
包括没有成功的医院外心肺复苏的患者,符合UDCD标准.
分析了心肺复苏开始,中期和入院时间,以及其他医院前的变量.

主要成果:

69个潜在的UDCD捐赠者:26个有效 (37.7%) 和43个无效 (62.3%).
在有效捐赠者 (26 mmHg) 与无效捐赠者 (15 mmHg;P<0.004) 抵达医院时的较高度值.
转移度的最佳切断值为17 mmHg. 机械胸部压缩,短暂的脉冲回归,较年轻的捐赠者年龄,以及更高的到达度独立预测了生存能力.

结论:

在抵达医院时进行透测量是识别可行的UDCD捐赠者的一个有价值的工具.
较年轻的捐赠者年龄,机械胸部压缩和短暂的脉回归是捐赠者生存能力的重要预测因素.

关键词:

大气量测量紧急情况暂时的脉冲恢复脉冲的暂时返回在循环死亡捐赠者后的无控制捐赠

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