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仅用于中脑膜动脉栓塞与慢性腹腔内血瘤的颗粒或液体栓塞剂
Adeline Fecker1, Matthew K McIntyre1, Huanwen Chen2
1Department of Neurological Surgery, Oregon Health and Science University, Portland, Oregon, USA.
Journal of neurointerventional surgery
|August 22, 2025
概括
线圈栓塞是一种安全有效的慢性皮下血瘤 (cSDH) 治疗方案,可与液体或颗粒剂相比较. 这种中脑膜动脉栓塞 (MMAE) 方法减少了与危险附带物相关的风险.
科学领域:
- 神经外科
- 干预性放射学
- 血管神经学
背景情况:
- 中脑膜动脉栓塞 (MMAE) 是慢性皮下血瘤 (cSDH) 的有效治疗方法.
- 使用颗粒或液体剂的传统MMAE具有通过危险的附带物而导致异位栓塞的理论风险.
- 作为一种潜在的更安全的替代方案,主要用于已确诊的血管瘤患者.
研究的目的:
- 为了比较单卷MMAE与cSDH液体或颗粒栓塞的安全性和有效性.
- 评估两种栓塞策略之间的手术救援率,血瘤吸收率和吸收率.
- 评估患有和没有危险血管瘤的患者的结局.
主要方法:
- 在2023年至2025年期间接受MMAE的168名cSDH患者的回顾性审查.
- 患者被分为"只有线圈" (88名患者) 和"液体/颗粒"栓塞组.
- 主要结果:手术救生率. 二次结局:血瘤再吸收量和速度. 对患有危险瘤的患者进行小组分析.
主要成果:
- 与液体/颗粒剂相比,仅用线圈栓塞的手术救治率没有显著差异 (5.7%与2. 5%,P=0. 52).
- 血瘤再吸收量和速率在不同组之间是相似的 (P>0.05).
- 在65名患有危险副作用的小组中没有观察到显著的结果差异 (P>0. 05).
结论:
- 只有线圈的MMAE是一种安全且同样有效的替代物,可用于cSDH的颗粒或液体栓塞.
- 在患有复杂血管解剖的患者中,这种方法可以减轻与非目标栓塞相关的风险.
- 进一步的研究可能会巩固单线栓塞作为选择cSDH患者的首选策略.
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