相关实验视频

Updated: Sep 10, 2025

Epicardial Outgrowth Culture Assay and Ex Vivo Assessment of Epicardial-derived Cell Migration

Epicardial Outgrowth Culture Assay and Ex Vivo Assessment of Epicardial-derived Cell Migration

Published on: March 18, 2016

以表心脂肪评估预测心血管风险

Giuseppe Calcaterra¹, Ron T Varghese², Maurizio Baroni³

¹Former Professor of Pediatric Cardiology, Postgraduate Medical School of Cardiology, University of Palermo, Italy.

European journal of internal medicine

|August 22, 2025

概括

皮心脂肪组织是一个独特的脂肪库, 提供心脏保护, 但可以成为有害的疾病. 它的测量是可靠的心血管风险标志物,也是新疗法的目标.

科学领域:

心脏病学
代谢研究
脂肪组织生物学

背景情况:

皮心脂肪组织 (EAT) 是一个独特的内脏脂肪储存,具有独特的解剖学和代谢特征.
EAT与心脏共享微循环,表明潜在的相互作用并影响心脏健康.
虽然EAT通常具有保护作用,但在病理条件下可能会对心肌和冠状动脉产生影响.

研究的目的:

审查心脏上脂肪组织在心脏风险中的作用的新证据.
强调EAT作为心脏病理发展的积极参与者.
讨论EAT作为心血管疾病的潜在可修改治疗点.

主要方法:

对心上脂肪组织的科学文献的综述.
对EAT的解剖学,代谢和转录特征的分析.
EAT测量与各种心血管和代谢疾病的相关性.

主要成果:

它具有与棕色脂肪相似的特性,具有代谢和心脏保护功能.
在晚期冠状动脉疾病中发生EAT转录基因的下调.
EAT厚度/体积测量与内脏脂肪,CAD,代谢综合征和心脏功能障碍相关.

结论:

皮心脂肪组织是心血管风险的可靠标志物.
EAT是心脏病学的积极参与者,也是潜在的治疗点.
改善血管化,减肥和药物等干预措施可以恢复EAT的保护功能.

关键词:

心血管疾病风险皮心脂肪组织流行病学心脏衰竭预防措施预测情况

更多相关视频

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Published on: September 22, 2020

Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome

Published on: September 27, 2024

相关概念视频

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...

Coronary Artery Disease I: Introduction

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...

Imaging Studies for Cardiovascular System III: X-Ray

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...

Assessment of the Cardiovascular System I: Subjective Data

Assessment of the Cardiovascular System I: Subjective Data

A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...