饮食炎症指数 (DII) 评分与儿童注意力缺陷多动症 (ADHD) 之间的关联
Fatemeh Navab1,2,3, Khadijeh Abbasi1,2, Hajar Heidari1,2
1Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Scientific reports
|August 22, 2025
概括
较高的能量调整的饮食炎症指数 (E-DII) 与伊朗儿童注意力缺陷多动症 (ADHD) 的风险增加有关. 这一发现表明饮食可能在ADHD的发展中起作用.
科学领域:
- 神经发育障碍
- 营养科学
- 儿童健康
背景情况:
- 注意缺陷多动性障碍 (ADHD) 是一种普遍存在的神经发育障碍,其病因不明.
- 诸如遗传,家族病史,营养,生活方式和炎症等因素都与ADHD的发展有关.
- 饮食炎症指数 (DII) 量化了饮食的炎症潜力.
研究的目的:
- 调查饮食炎症指数 (DII) 与儿童多动症风险之间的联系.
- 确定饮食的炎症潜力是否与儿童群体的多动症有关.
主要方法:
- 一项涉及500名伊朗4至12岁儿童的病例对照研究 (ADHD患者200人,健康对照患者300人).
- 使用168项食物频率问卷 (FFQ) 评估饮食摄入量;计算了能量调整的DII (E-DII) 评分.
- 统计分析包括ANCOVA和多变量逻辑回归,调整年龄,性别,收入和BMI.
主要成果:
- 经过能量调整的饮食炎症指数 (E-DII) 显示与ADHD风险有显著的直接关联.
- 在原始,模型1和模型2分析中,ADHD的几率比率 (ORs) 增加了 (p < 0. 05).
- 具体来说,ORs在1.104到1.162之间,这表明有更多的促炎饮食会增加风险.
结论:
- 在伊朗儿童中,E-DII分数的升高与ADHD的风险显著增加有关.
- 具有较高炎症潜力的饮食模式可能会导致ADHD的发展.
- 鉴于研究的局限性,需要进一步的研究来证实这些发现并探索因果关系.
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