尼日利亚人体免疫缺陷病毒感染者的患病率和心血管疾病风险预测因素
Abiodun Isah1, Olujuwon Ibiloye2,3, Temiwoluwa Omole2
1APIN Public Health Initiatives, Plot 1551, Zone E, Apo Resettlement, Apo, Abuja, Ogun State, Nigeria. aisah@apin.org.ng.
AIDS research and therapy
|August 22, 2025
概括
尼日利亚艾滋病毒感染者心血管疾病的风险很高, 需要综合干预来应对日益严重的健康问题.
科学领域:
- 公共卫生
- 流行病学
- 传染性疾病
背景情况:
- 艾滋病毒/艾滋病的治疗得到了改善,使艾滋病毒成为一种可控的慢性疾病.
- 非传染性疾病,特别是心血管疾病,在艾滋病毒感染者 (PLHIV) 中越来越普遍.
- 这一趋势在发展中国家尤为明显,
研究的目的:
- 确定尼日利亚艾滋病毒感染者心血管疾病 (CVD) 风险的患病率.
- 确定与该人群中心血管疾病风险增加相关的人口,临床和生活方式因素.
- 为PLHIV预防和管理提供有针对性的干预措施.
主要方法:
- 在2024年2月至5月期间,尼日利亚十个卫生机构进行了横截面研究.
- 通过问卷和医疗记录收集的数据,纳入了1000名接受抗逆转录病毒治疗的PLHIV患者.
- 统计分析包括基平方测试和逻辑回归 (SPSS v24),在p < 0.05时具有显著性.
主要成果:
- 研究群体的中位数年龄为48岁,女性占60. 7%. 常见的疾病包括高血压 (26. 2%),超重 (27. 9%) 和肥胖 (19. 6%).
- 总的来说,61. 1% 的PLHIV患者被确定为患心血管疾病的风险.
- 较高心脏病风险的重要预测因素包括城市居住,吸烟,家族血压高,治疗时间较长 (≥10年),以及不经常食用高脂肪,高糖和高盐食物.
结论:
- 心血管疾病 (CVD) 风险是尼日利亚艾滋病毒感染者 (PLHIV) 的重要和普遍问题.
- 人口,临床 (例如ART治疗时间) 和生活方式 (例如吸烟,饮食) 是心血管疾病风险的关键决定因素.
- 针对性,综合性和以客户为中心的干预措施对于减轻PLHIV患者心血管疾病负担至关重要.
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