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Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag
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KLHL23和RhoGDI协调CDC42不活化,确保膜平衡

Po-Cheng Liao1,2, Hao-Chun Chang1, Yi-Chung Liu3

  • 1Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.

Nature chemical biology
|August 22, 2025
PubMed
概括

KLHL23/RhoGDI-CDC42通路通过禁用CDC42来控制细胞迁移. 破坏这一轴会促进转移, 突显其治疗潜力.

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