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Updated: Sep 10, 2025

Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method
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Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method

Published on: October 23, 2018

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在人类癌症中,α-谷氨酸决定了AMPK蛋白合成的能量感应

Wen Mi1, Yun Xue2, Haohang Yan1

  • 1Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology; Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.

Nature chemical biology
|August 22, 2025
PubMed
概括

代谢物α- ketoglutarate (α- KG) 通过TET- YBX1通路调节AMP激活蛋白激酶 (AMPK) 的翻译. 准这一轴使得癌细胞对能量压力敏感,

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