肠道营养方案对神经科重症监护室患者的营养指标和预后的影响:随机对照试验
Xia Zhang1, Jun Zhang1, Zhi-Bo You2
1Department of Neurology, Affiliated Hospital of Zunyi Medical University, Zunyi, 563000, Guizhou, China.
将乳清蛋白和Bifidobacterium添加到肠道营养中可以改善营养,并减少神经病重症监护室患者的并发症. 综合治疗 (肠道营养 + Bifidobacterium + 乳清蛋白) 显示出对患者预后的最佳结果.
科学领域:
- 危急护理医学
- 营养科学
- 胃肠病学
背景情况:
- 肠道营养对于重症患者至关重要.
- 神经科重症监护室患者经常面临营养状况和并发症的挑战.
- 优化肠道营养可以改善患者的结果.
研究的目的:
- 评估乳清蛋白和Bifidobacterium补充剂对接受肠道营养的神经科重症监护室患者的影响.
- 比较不同补充策略对营养指标,并发症和预后的影响.
- 确定最佳组合以改善患者的治疗结果.
主要方法:
- 100名神经科重症监护室患者被随机分为四组:只有肠道营养 (EN),EN + Bifidobacterium,EN + Bifidobacterium + 乳清蛋白和EN + 乳清蛋白.
- 评估了营养标志物 (白蛋白,总蛋白,前白蛋白),并发症率 (腹,胃问题),预后指标 (住院,感染) 和APACHE II分数.
- 数据收集时间为7天.
主要成果:
- 与单独使用EN相比,补充乳清蛋白和Bifidobacterium显著改善了营养指标.
- 在营养状况和减少腹和胃出血方面,EN + Bifidobacterium + 乳清蛋白 (EN3) 的组合显示出优异的结果.
- 在APACHE II分数和肺部感染率中,EN3也显著改善,导致抗生素使用量减少.
结论:
- 用乳清蛋白和Bifidobacterium quadruplex补充肠道营养可以有效地改善神经病重症监护室患者的营养状况.
- 这种综合方法显著减少了胃肠道并发症,并改善了患者的整体预后.
- 用Bifidobacterium和乳清蛋白进行肠道营养的结合为神经病重症患者提供了最显著的好处.
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