中年和老年印度人脂质异常的农村和城市差异
Priya Chatterjee1,2, Sakshi Arora1, Pooja Rai1
1Centre for Brain Research, Indian Institute of Science, Bangalore, 560012, India.
城市地区的总胆固醇和LDL胆固醇水平较高. 农村地区的高胆固醇和高胆固醇水平较低, 表明需要针对性的干预措施.
科学领域:
- 心脏病学
- 公共卫生
- 老年学
背景情况:
- 脱脂症是心血管疾病 (CVD) 的重要危险因素.
- 脱脂症的发病率通常在地理位置上有所不同,在城市环境中发病率更高.
- 这项研究调查了印度老龄化人口的脂质障碍,比较农村和城市的脂质异常.
研究的目的:
- 确定印度老龄化人口中脱脂症的患病率.
- 为了比较农村和城市的脂质异常.
- 在这些人群中确定与脱脂症相关的危险因素.
主要方法:
- 分析了印度南部2,797名农村和430名城市参与者的基线数据.
- 使用标准实验室技术测量脂质概况;根据NCEP ATP-III标准分类异常.
- 使用Z测试和多变量逻辑回归的风险因子分析对脂质异常比例进行比较.
主要成果:
- 在城市人口中,高总胆固醇 (37.0%对28.4%) 和LDL-c (33.5%对26.8%) 的患病率较高.
- 农村人口呈现较高的低HDL-c (72. 4%对比44. 2%),高的甘油三 (45. 7%对比38. 6%) 和升高的脂质风险比率.
- 在这两种情况下,女性患多种脂质异常的风险更高;糖尿病,超重,肥胖和不活动与脂质问题有关,而在城市地区则较少.
结论:
- 农村和城市的老年印度人都有很高的脂质异常.
- 增加心血管疾病的风险需要有针对性的干预措施来减轻这些社区的疾病负担.
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