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叙利亚战争期间卵巢癌的流行病学和临床病理学特征:全国多中心回顾性研究 (2017-2021年)
Shant Apelian1,2, Alaa Hamdan3,4, Rita Mohammad3,5
1Department of Obstetrics and Gynecology, Tishreen University Hospital, Latakia, Syria. apelianshant@gmail.com.
BMC cancer
|August 23, 2025
概括
这项研究分析了叙利亚的卵巢癌,发现血清性癌症是最常见的,腹部膨胀是常见的症状. 较低的OC诊断可能反映冲突地区报告不足和获得医疗保健的问题.
科学领域:
- 癌症学
- 流行病学
- 公共卫生
背景情况:
- 卵巢癌在全球造成重大健康负担, 叙利亚等受冲突影响地区的数据有限.
- 了解叙利亚的疾病流行病学是非常重要的,因为冲突对医疗保健的影响和地区的变化.
研究的目的:
- 在叙利亚进行第一个全国性卵巢癌 (OC) 流行病学和临床病理学特征分析.
- 确定叙利亚人口中常见的OC亚型,表现出症状和相关因素.
主要方法:
- 在叙利亚的三所高等推大学医院进行了一项全国性,多中心的回顾性横截面研究.
- 分析了2017年至2021年间新诊断的531名18岁以上的卵巢癌患者的数据.
- 收集了社会人口统计信息,症状,CA-125水平和治疗细节.
主要成果:
- 血清癌是最常见的OC亚型 (55. 4%),其次是粘膜癌 (13. 8%) 和子宫内膜癌 (9. 7%).
- 高CA-125水平与血清性癌症的可能性增加 (aOR: 2. 30) 和子宫内膜癌的可能性降低 (aOR: 0. 21).
- 腹部膨胀是最常见的症状,报告了36. 5%的患者.
结论:
- 该研究发现,与全球数据相比,叙利亚的卵巢癌诊断比例较低,这可能是由于报告不足和医疗保健获取障碍.
- 调查结果强调需要进一步的研究,以全面评估受冲突影响的叙利亚境内OC负担.
- 解决医疗服务障碍对于叙利亚的确切诊断和管理至关重要.
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