美国私人保险成人的BRCA遗传检测使用和支出,2013-2022年
Lu Shi1, Katherine Kolor2, Zhuo Chen3
1Center for the Evaluation of Value and Risk in Health, Tufts Medical Center, Boston, MA, USA.
概括
女性和男性的BRCA检测使用量增加,成本大幅下降. 根据家庭和个人病史, 扩展的指导方针现在涵盖了更多的个人, 强调其作为预防服务的作用.
科学领域:
- 遗传学和基因组学
- 预防医学
- 医疗服务研究
背景情况:
- 最近的临床指导方针扩大了BRCA咨询和测试的适用范围.
- 现在的标准包括家庭病史,个人病史以及女性和男性的乳腺癌,卵巢癌,胰腺癌和前列腺癌的诊断.
研究的目的:
- 评估BRCA检测的使用,支出和自付成本.
- 根据性别,年龄和大都市地位检查BRCA测试的趋势.
主要方法:
- 对于18至64岁的持续注册个人,对2013年至2022年的索赔数据进行分析.
- 使用程序编码确定BRCA测试,以评估年度使用和支出.
- 检查零自付费用 (OOP) 和测试指示.
主要成果:
- 女性和男性每年使用BRCA测试的比例有所增加,每年增长率显著.
- 2020年检测利用率下降,但反弹,尽管在2022年仍低于疫情前的水平.
- 从2013年至2022年,BRCA检测的中位数支出下降了68%,大多数注册者没有OOP成本.
- 测试主要由乳腺,卵巢或前列腺癌的家族史驱动,特别是在18-50岁的女性中.
结论:
- 有知识的医疗保健提供者对于确保符合条件的个人获得生殖基因 BRCA 检测至关重要.
- 根据不断变化的临床指导方针,BRCA检测是重要的预防服务.
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