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Updated: Sep 10, 2025

Analysis of Fucosylated Human Milk Trisaccharides in Biotechnological Context Using Genetically Encoded Biosensors
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一个针对细胞表面的化探针用于检测硫酶2活性

Yi Ding1, Toshiyuki Kowada1,2, Toshitaka Matsui1,2

  • 1Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577, Japan.

Bioconjugate chemistry
|August 23, 2025
PubMed
概括

研究人员开发了一种新型化探针MAR-S,用于监测活细胞中的硫酶2 (Sulf-2) 活性. 通过可视化酶活性,该工具有助于与硫-2-相关的癌症诊断和治疗研究.

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相关概念视频

Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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