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转录因子TFAP2A通过激活PRAME转录来驱动三阴性乳腺癌的生长和转移,并阻断铁

Bei Pei1, Huiting Sun2, Lingyun Xu3

  • 1The Second People's Hospital of Changzhou, the Third Affiliated Hospital of Nanjing Medical University, Changzhou, China.

Naunyn-Schmiedeberg's archives of pharmacology
|August 23, 2025
PubMed
概括

转录因子AP-2α (TFAP2A) 通过激活PRAME,抑制铁死,促进三阴性乳腺癌 (TNBC) 的进展. 针对TFAP2A和PRAME提供了一个潜在的TNBC治疗策略.

关键词:
铁症侵袭这是一个很好的例子.其他国家在TNBC

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