新的光学测试系统用于使用铁与2.2'-双衍生物复合物的抗氧化能力
Elena Salimgareeva1, Maria Konovalova1, Maria Lykova1
1Department of Chemical Technology, Ural Federal University, 620002 Ekaterinburg, Russia.
Journal of inorganic biochemistry
|August 23, 2025
概括
本研究提出了一种新的半定量光学测试系统,用于测量抗氧化能力 (AOC). 该系统使用协调化合物和颜色比较传感器进行各种物质的快速,准确的现场分析.
科学领域:
- 分析化学
- 材料科学
- 生物化学
背景情况:
- 评估抗氧化能力 (AOC) 对于评估物质对氧化应激的保护作用至关重要.
- 现有的AOC测定方法可能耗时,需要专门的实验室设备.
- 对于各种应用来说,开发快速,可移植和准确的AOC评估方法是非常可取的.
研究的目的:
- 引入一种新的半定量光学测试系统来确定各种物质的抗氧化能力 (AOC).
- 开发和验证使用协调化合物作为模型氧化剂和基于纸张的传感器的系统.
- 能够准确地在现场分析抗氧化剂活性.
主要方法:
- 开发一个含有塑料板和纸质传感器的半定量光学测试系统,其中含有模拟氧化剂和校准条.
- 通过"1,2,4-triazine"方法合成的含有2,2-二氧化衍生物的铁复合物作为模型氧化剂.
- 使用基于Python的软件进行增强的颜色识别,并开发了用于传感器颜色比较的校准条.
- 复杂化合物的评估性质 (稳定性,分子吸收性,溶解性) 在溶液和薄层中.
主要成果:
- 已确定具有高稳定性,对比性和溶解性的有前途的铁-2,2'-二胺复合物,适用于便携式设备.
- 证明了该系统能够确定含有 Askorbic 酸和α-tocopherol 的模型抗氧化剂溶液,植物提取物和补充剂的 AOC.
- 在开发的测试系统和常规光谱测量结果之间取得了很高的一致性.
结论:
- 开发的半定量光学测试系统提供了一种可靠的方法,用于对抗氧化能力进行快速和准确的现场分析.
- 该系统的设计,利用稳定和可溶的协调化合物,促进其在便携式分析设备中的使用.
- 这种创新方法扩大了对各种物质抗氧化性能的分析范围.
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