营养感应受体GPRC6A调节mTORC1信号和tau生物

Chao Ma1, Kelsey Campbell2, Andrii Kovalenko3

  • 1Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States; Sanders-Brown Center on Aging, Department of Neuroscience, College of Medicine, University of Kentucky, Lexington, KY, United States.

Neurobiology of disease
|August 23, 2025
PubMed
概括

在病症中,氨酸感知途径对拉巴胺复合体1 (mTORC1) 信号的机制性位进行调节. 向G蛋白结合受体6C (GPRC6A) 减少tau的积累,为阿尔茨海默病和相关疾病提供潜在的治疗策略.

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