用于通过暗发酵从草药残留物生产的多多巴胺修饰泡铁
Zheng Dong1, Shengxian Cao1, Gong Wang1
1School of Automation Engineering, Northeast Electric Power University, Jilin 132012, China.
Bioresource technology
|August 23, 2025
概括
聚多巴胺修饰泡铁 (PDA-FI) 通过增强有益微生物和抑制有害微生物,增加了25.1%的暗发酵产量. 这种新材料为利用草药残留物提供了具有成本效益的解决方案.
科学领域:
- 生物技术
- 环境科学
- 材料科学
背景情况:
- 草药残留物在清洁利用方面存在挑战.
- 暗发酵是产生的关键过程.
研究的目的:
- 开发和评估一种聚多巴胺修饰的泡铁 (PDA-FI) 材料,用于增强暗发酵的产生.
- 在这个过程中阐明PDA-FI的代谢调节机制.
主要方法:
- 单因素实验与极端学习机器-贝叶斯优化相结合,以实现过程优化.
- 微生物群体分析以评估细菌群体的变化.
- 基因表达分析以调查代谢途径.
主要成果:
- 在使用PDA-FI的最佳条件下,累计气产量增加了25.1%.
- PDA-FI增强了产生的Clostridium_sensu_stricto_1的相对丰度,同时抑制了产生乳酸的Escherichia-Shigella.
- 观察到关键的Butyrate合成和酶活性代谢基因的激活.
结论:
- PDA-FI是一种高效的功能性载体材料,用于暗发酵.
- PDA-FI显示了草药残留的清洁利用和增强生产的广泛应用前景.
相关概念视频
Microbes in Food Production
403
Microbial fermentation is central to food biotechnology, enhancing flavor, texture, preservation, and stability. Fermentative microorganisms metabolize carbohydrates into organic acids, alcohols, and other metabolites that inhibit spoilage organisms and improve digestibility while contributing distinctive sensory qualities.In baking, amylases naturally present in flour hydrolyze starch into monosaccharides such as glucose, which Saccharomyces cerevisiae ferments anaerobically. Through...
403
Microbes in Beverage Production
298
Alcoholic beverages such as wine, beer, and spirits are the products of microbial fermentation processes that transform simple sugars into ethanol and a wide array of complex flavor compounds. These transformations rely on the metabolic activities of specific yeasts and bacteria, which are selected and controlled to yield the desired beverage characteristics.Wine Fermentation and MaturationWine production begins with the crushing of grapes to release juice and pulp, forming a must that is...
298
Microbes in the Production of Fermented Foods
327
Lactic acid bacteria (LAB) and molds are instrumental in fermenting plant-based foods to enhance preservation and ensure year-round availability. These microbial processes convert plant carbohydrates into organic acids and other metabolites that inhibit spoilage organisms and contribute to the sensory qualities of the final product.In sauerkraut production, cabbage goes through a microbial succession that starts with cocci such as Leuconostoc mesenteroides. These microbes begin fermentation by...
327
Production of Organic Acids
105
Lactic acid, an important organic acid extensively applied in food, pharmaceutical, and biodegradable polymer industries, is primarily produced via microbial fermentation. This method is favored over chemical synthesis due to its environmental sustainability and capacity for enantiomerically pure product formation. Among various microbial processes, the fermentation of starch-based substrates stands out due to the abundance and renewability of raw materials like corn and potatoes.Hydrolysis of...
105
Production of Antibiotics
265
Penicillin, one of the earliest and most widely used antibiotics, is produced industrially by the filamentous fungus Penicillium chrysogenum. Large stirred-tank bioreactors ranging from tens to hundreds of thousands of liters maintain tightly controlled temperature, pH, and dissolved oxygen conditions to support fungal metabolism and maximize antibiotic yield. Penicillin is a secondary metabolite, synthesized primarily during the stationary growth phase, which requires a carefully managed...
265
Production of Pharmaceuticals
94
Industrial insulin production uses genetically engineered E. coli expressing a proinsulin gene controlled by a tryptophan promoter and containing a methionine linker for later cleavage. The cells also carry ampicillin resistance for selective growth. Seed cultures are stored at −80 °C and production begins by thawing a small amount to inoculate starter cultures, which are progressively scaled to a 50,000-L bioreactor. In the bioreactor, E. coli grow in nutrient-rich media under...
94


