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Updated: Sep 10, 2025

Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
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基于 ToxCast 数据的集群阅读识别出布洛菲津是一种具有肥胖潜力的部分 PPARγ 激动剂

Seokyoung Hwang1, Soyeon Oh1, Seungchan An1

  • 1College of Pharmacy, Natural Products Research Institute, Seoul National University, 1 Gwanak-ro, Seoul, Gwanak-gu 08826, Republic of Korea.

Toxicology letters
|August 23, 2025
PubMed
概括

环境中的肥胖因子, 促进肥胖的化学物质, 越来越令人担忧. 通过分析其对脂质代谢和PPARγ活性的影响,该研究确定了昆虫杀虫剂布洛菲津是潜在的肥胖原体.

关键词:
布普罗菲津基于集群的交叉读取环境肥胖剂PPARγ部分激动剂这是一个很好的机会.

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Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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